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Journal article

Col1a2 enhancer regulates collagen activity during development and in adult tissue repair.

Abstract:

An enhancer region in the type I collagen alpha 2 chain (pro-Col1a2) promoter has been previously identified approximately -17 kb away from the transcription start site. This upstream region termed the far-upstream-enhancer contains three DNAse I hypersensitive sites and has been shown to be conserved between mouse and human genes. In this study, we used transgenic mice harbouring the complete promotor sequence of the pro-Col1a2 gene up to -17 kb to examine the role of this enhancer in the ex...

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Publication status:
Published

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Journal:
Matrix biology : journal of the International Society for Matrix Biology
Volume:
22
Issue:
8
Pages:
619-628
Publication date:
2004-02-01
DOI:
EISSN:
1569-1802
ISSN:
0945-053X
Source identifiers:
223492

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