Journal article
Valuation and modeling of EQ-5D-5L health states using a hybrid approach.
- Abstract:
-
Background
The EQ-5D instrument is the most widely used preference-based health-related quality of life questionnaire in cost-effectiveness analysis of health care technologies. Recently, a version called EQ-5D-5L with 5 levels on each dimension was developed. This manuscript explores the performance of a hybrid approach for the modelling of EQ-5D-5L valuation data.
Methods
Two elicitation techniques, the composite time trade-off (C-TTO), and discrete choice (DC) experiments, were applied to a sample of the Spanish population (n = 1,000) using a computer-based questionnaire. The sampling process consisted of two stages: stratified sampling of geographic area, followed by systematic sampling in each area. A hybrid regression model combining C-TTO and DC data was used to estimate the potential value sets using main effects as starting point. The comparison between the models was performed using the criteria of logical consistency, goodness of fit and parsimony.
Results
27 participants from the 1,000 were removed following the exclusion criteria. The best-fitted model included two significant interaction terms but resulted in marginal improvements in model fit compared to the main effects model. We therefore selected the model results with main effects as a potential value set for this methodological study, based on the parsimony criteria. The results showed that the main effects hybrid model was consistent, with a range of utility values between 1 and -0.224.
Conclusions
This paper shows the feasibility of using a hybrid approach to estimate a value set for EQ-5D-5L valuation data.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 173.0KB, Terms of use)
-
- Publisher copy:
- 10.1097/mlr.0000000000000283
Authors
- Publisher:
- Lippincott, Williams & Wilkins
- Journal:
- Medical Care More from this journal
- Volume:
- 55
- Issue:
- 7
- Pages:
- e51-e58
- Publication date:
- 2017-07-01
- Acceptance date:
- 2014-10-22
- DOI:
- EISSN:
-
1537-1948
- ISSN:
-
0025-7079
- Pmid:
-
25521503
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:502052
- UUID:
-
uuid:c7f58cb3-af97-4e4a-bf1f-486af727b1fe
- Local pid:
-
pubs:502052
- Source identifiers:
-
502052
- Deposit date:
-
2017-08-23
Terms of use
- Copyright holder:
- Ramos-Goñi et al
- Copyright date:
- 2017
- Notes:
-
Copyright © 2014 The Author(s). Published by Wolters Kluwer Health, Inc.
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
If you are the owner of this record, you can report an update to it here: Report update to this record