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A simple cognitive task intervention to prevent intrusive memories after trauma in patients in the emergency department: a randomized controlled trial terminated due to COVID-19

Abstract:

Objective: This randomised controlled trial (RCT) aimed to investigate the effects of a simple cognitive task intervention on intrusive memories ("flashbacks") and associated symptoms following a traumatic event. Patients presenting to a Swedish emergency department (ED) soon after a traumatic event were randomly allocated (1:1) to the simple cognitive task intervention (memory cue + mental rotation instructions + computer game "Tetris" for at least 20 min) or control (podcast, similar time). We planned follow-ups at one-week, 1-month, and where possible, 3- and 6-months post-trauma. Anticipated enrolment was N = 148.

Results: The RCT was terminated prematurely after recruiting N = 16 participants. The COVID-19 pandemic prevented recruitment/testing in the ED because: (i) the study required face-to-face contact between participants, psychology researchers, ED staff, and patients, incurring risk of virus transmission; (ii) the host ED site received COVID-19 patients; and (iii) reduced flow of patients otherwise presenting to the ED in non-pandemic conditions (e.g. after trauma). We report on delivery of study procedures, recruitment, treatment adherence, outcome completion (primary outcome: number of intrusive memories during week 5), attrition, and limitations. The information presented and limitations may enable our group and others to learn from this terminated study.

Trial registration: ClinicalTrials.gov: NCT04185155 (04-12-2019)

Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1186/s13104-021-05572-1

Authors

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Role:
Author
ORCID:
0000-0003-0148-7247


Publisher:
Springer
Journal:
BMC Research Notes More from this journal
Volume:
14
Issue:
1
Article number:
176
Publication date:
2021-05-10
Acceptance date:
2021-04-15
DOI:
EISSN:
1756-0500
Pmid:
33971951


Language:
English
Keywords:
Pubs id:
1180062
Local pid:
pubs:1180062
Deposit date:
2025-04-17
ARK identifier:

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