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A lack of commitment for over 500 million years: conserved animal stem cell pluripotency.

Abstract:

Stem cells, both adult and germline, are the key cells underpinning animal evolution. Yet, surprisingly little is known about the evolution of their shared key feature: pluripotency. Now using genome-wide expression profiling of pluripotent planarian adult stem cells (pASCs), Önal et al (2012) present evidence for deep molecular conservation of pluripotency. They characterise the expression profile of pASCs and identify conserved expression profiles and functions for genes required for mammal...

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Publisher copy:
10.1038/emboj.2012.131

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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
Journal:
The EMBO journal
Volume:
31
Issue:
12
Pages:
2747-2749
Publication date:
2012-06-05
DOI:
EISSN:
1460-2075
ISSN:
0261-4189
URN:
uuid:c7c23a7a-2443-48e8-aa8c-00043dd51675
Source identifiers:
375945
Local pid:
pubs:375945

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