- Abstract:
-
Stem cells, both adult and germline, are the key cells underpinning animal evolution. Yet, surprisingly little is known about the evolution of their shared key feature: pluripotency. Now using genome-wide expression profiling of pluripotent planarian adult stem cells (pASCs), Önal et al (2012) present evidence for deep molecular conservation of pluripotency. They characterise the expression profile of pASCs and identify conserved expression profiles and functions for genes required for mammal...
Expand abstract - Publisher copy:
- 10.1038/emboj.2012.131
-
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- Journal:
- The EMBO journal
- Volume:
- 31
- Issue:
- 12
- Pages:
- 2747-2749
- Publication date:
- 2012-06-05
- DOI:
- EISSN:
-
1460-2075
- ISSN:
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0261-4189
- URN:
-
uuid:c7c23a7a-2443-48e8-aa8c-00043dd51675
- Source identifiers:
-
375945
- Local pid:
- pubs:375945
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
A lack of commitment for over 500 million years: conserved animal stem cell pluripotency.
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