Electrical estimulation of retinal pigment epithelial cells.

Journal article

We investigated and characterized the effect of externally applied electric fields (EF) on retinal pigment epithelial (RPE) cells by exposing primary cultures of human RPE cells (hRPE) and those from the ARPE19 immortalized cell line to various strengths of EF (EF-treated cells) or to no EF (control cells) under different conditions including presence or absence of serum and gelatin and following wounding. We evaluated changes in RPE cell behavior in response to EF by using a computer based i...

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Authors: Gamboa, O; Pu, J; Townend, J; Forrester, J; Zhao, M

• Publication status: Published
• Journal: Experimental eye research
• Volume: 91
• Issue: 2
• Pages: 195-204
• Publication date: 2010-08-01
• DOI: 10.1016/j.exer.2010.04.018
• EISSN: 1096-0007
• ISSN: 0014-4835
• Language: English
• Keywords: Electric Stimulation; Gelatin; Serum; Aged; Humans; Cell Polarity; Retinal Pigment Epithelium; Cell Line, Transformed; Cell Proliferation; Male; Cell Survival; Cells, Cultured; Cell Movement; Electromagnetic Fields; Aged, 80 and over; Image Processing, Computer-Assisted; Wound Healing