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Cost-Utility of Attachment-Based Compassion Therapy (ABCT) and Mindfulness-Based Stress Reduction (MBSR) in the Management of Depressive, Anxious, and Adjustment Disorders in Mental Health Settings: Economic Evaluation Alongside a Randomized Controlled Trial

Abstract:
Objectives: The main objective of this paper was to examine the cost-utility of attachment-based compassion therapy (ABCT) compared to Mindfulness-Based Stress Reduction (MBSR) and treatment-as-usual (TAU) on patients with depressive and/or anxious disorder, or adjustment disorder with depressive and/or anxious symptomatology in terms of effects on quality-adjusted life years (QALYs) as well as healthcare costs from a public healthcare system perspective. Method: A 6-month randomized controlled trial was conducted. Ninety Spanish patients with mental disorders (depressive, anxious, or adjustment disorders) received 8 weekly group sessions of TAU + ABCT, TAU + MBSR, or TAU alone. Data collection took place at pre- and 6-month follow-up. Cost-utility of the two treatment groups (ABCT vs MBSR vs TAU) was compared by examining treatment outcomes in terms of QALYs (obtained with the EQ-5D-3L) and healthcare costs (data about service use obtained with the Client Service Receipt Inventory). Results: Both MBSR and ABCT were more efficient than TAU alone, although the results did not reach statistical significance. Compared to ABCT, MBSR produced an increase both in terms of costs (€53.69, 95% CI [− 571.27 to 513.14]) and effects (0.004 QALYs, 95% CI [− 0.031 to 0.049]); ICUR = €13,422.50/QALY). Both interventions significantly reduced the number of visits to general practice compared to TAU. Conclusions: This study has contributed to the evidence base of mindfulness- and compassion-based programs and provided promising information about the cost-utility of MBSR for patients with emotional disorders. However, the small sample size and short follow-up period limit the generalizability of the findings. Preregistration: Clinicaltrials.gov; NCT03425487
Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0002-9482-4822
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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0001-5677-1662


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Funder identifier:
10.13039/501100004587
Grant:
CB22/02/00052
CD20/00181
CP21/00080
RD21/0016/0005
CB22/02/00052
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Funder identifier:
10.13039/501100011104


Publisher:
Springer
Journal:
Mindfulness More from this journal
Volume:
15
Issue:
3
Pages:
559-569
Publication date:
2024-03-04
DOI:
EISSN:
1868-8535
ISSN:
1868-8527


Language:
English
Keywords:
Pubs id:
1851315
Local pid:
pubs:1851315
Source identifiers:
W4392401902
Deposit date:
2026-06-09
ARK identifier:
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