- Abstract:
-
The relationship between the function of human immunodeficiency virus (HIV)-specific CD8 T-cell responses and viral load has not been defined. In this study, we used a panel of major histocompatibility complex class I tetramers to examine responses to frequently targeted CD8 T-cell epitopes in a large cohort of antiretroviral-therapy-naïve HIV type 1 clade C virus-infected persons in KwaZulu Natal, South Africa. In terms of effector functions of proliferation, cytokine production, and degranu...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1128/jvi.01754-06
-
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- Journal:
- Journal of virology
- Volume:
- 81
- Issue:
- 1
- Pages:
- 434-438
- Publication date:
- 2007-01-05
- DOI:
- EISSN:
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1098-5514
- ISSN:
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0022-538X
- URN:
-
uuid:c7717a2c-2d51-46eb-bbe5-795e86c875b8
- Source identifiers:
-
29495
- Local pid:
- pubs:29495
- Copyright date:
- 2007
Journal article
Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection.
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