On-lattice agent-based simulation of populations of cells within the open-source chaste framework

Journal article

Over the years, agent-based models have been developed that combine cell division and reinforced random walks of cells on a regular lattice, reaction-diffusion equations for nutrients and growth factors and ordinary differential equations (ODEs) for the subcellular networks regulating the cell cycle. When linked to a vascular layer, this multiple scale model framework has been applied to tumour growth and therapy. Here we report on the creation of an agent-based multiscale environment amalgam...

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Authors: Figueredo, G; Joshi, T; Osborne, J; Byrne, H; Owen, M

• Publication date: 2012-01-01