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Multimodal neuroimaging correlates of physical-cognitive covariation in Chilean adolescents. The Cogni-Action Project

Abstract:
Health-related behaviours have been related to brain structural features. In developing settings, such as Latin America, high social inequality has been inversely associated with several health-related behaviours affecting brain development. Understanding the relationship between health behaviours and brain structure in such settings is particularly important during adolescence when critical habits are acquired and ingrained. In this cross-sectional study, we carry out a multimodal analysis identifying a brain region associated with health-related behaviours (i.e., adiposity, fitness, sleep problems and others) and cognitive/academic performance, independent of socioeconomic status in a large sample of Chilean adolescents. Our findings suggest that the relationship between health behaviours and cognitive/academic performance involves a particular brain phenotype that could play a mediator role. These findings fill a significant gap in the literature, which has largely focused on developed countries and raise the possibility of promoting healthy behaviours in adolescence as a means to influence brain structure and thereby cognitive/academic achievement, independently of socioeconomic factors. By highlighting the potential impact on brain structure and cognitive/academic achievement, policymakers could design interventions that are more effective in reducing health disparities in developing countries.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.dcn.2024.101345

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0002-9940-507X
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Oxford college:
St Edmund Hall
Role:
Author
ORCID:
0000-0002-4134-9730
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0003-3947-9541


More from this funder
Funder identifier:
https://ror.org/029chgv08
Grant:
203139/A/16/Z
110027/Z/15/Z


Publisher:
Elsevier
Journal:
Developmental Cognitive Neuroscience More from this journal
Volume:
66
Article number:
101345
Publication date:
2024-01-17
Acceptance date:
2024-01-13
DOI:
EISSN:
1878-9307
ISSN:
1878-9293
Pmid:
38277711


Language:
English
Keywords:
Pubs id:
1611568
Local pid:
pubs:1611568
Deposit date:
2025-02-20
ARK identifier:

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