Thesis
An investigation of the highly conserved long non-coding RNA CEROX1
- Abstract:
-
Amid growing catalogues of long non-coding RNAs (lncRNAs), experimentally characterised examples are few, especially for the recently identified subpopulation that are enriched in the cytoplasm. Amongst these are lncRNAs whose activity is proposed to be mediated by the competitive endogenous RNA (ceRNA) mechanism. De-repression of miRNA targets results in concerted gene expression changes following ceRNA modulation in numerous in vitro models, but evidence of in vivo physiological rele...
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Authors
Contributors
+ Sirey, TM
Department:
IGMM, University of Edinburgh
Role:
Supervisor
+ Ponting, CP
Department:
IGMM, University of Edinburgh
Role:
Supervisor
+ Davies, KE
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Supervisor
+ Oliver, PL
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Supervisor
+ Wood, MJA
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Examiner
Funding
+ Medical Sciences Division, University of Oxford
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Funding agency for:
Roberts, K
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- UUID:
-
uuid:c736f0f6-8879-4d42-900f-7cce98e52ca8
- Deposit date:
- 2020-02-11
Related Items
Terms of use
- Copyright holder:
- Roberts, K
- Copyright date:
- 2018
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