- Abstract:
-
Many basal ganglia neurodevelopmental disorders are thought to result from imbalances in the activity of the D1‐expressing direct‐pathway and D2‐expressing indirect‐pathway striatal projection neurons (SPNs). Insight into these disorders is reliant on our understanding of normal D1 and D2 SPN development. Here we provide the first detailed study and quantification of the striatal cellular and circuit changes occurring for both D1 and D2 SPNs in the first postnatal weeks using in vitro whole‐c...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
-
(pdf, 6.5mb)
-
- Publisher copy:
- 10.1113/jp278416
-
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- Publisher:
- Wiley Publisher's website
- Journal:
- The Journal of Physiology Journal website
- Volume:
- 597
- Issue:
- 21
- Pages:
- 5265-5293
- Publication date:
- 2019-09-18
- Acceptance date:
- 2019-09-04
- DOI:
- EISSN:
-
1469-7793
- ISSN:
-
0022-3751
- Pubs id:
-
pubs:1055444
- URN:
-
uri:c6fd1a50-d5fc-4466-be8b-1ee75afcafc6
- UUID:
-
uuid:c6fd1a50-d5fc-4466-be8b-1ee75afcafc6
- Local pid:
- pubs:1055444
- Language:
- English
- Keywords:
- Copyright holder:
- Krajeski et al.
- Copyright date:
- 2019
- Notes:
- © 2019 The Authors. The Journal of Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Journal article
Dynamic postnatal development of the cellular and circuit properties of striatal D1 and D2 spiny projection neurons
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