Journal article icon

Journal article

MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment

Abstract:

The molecular mechanisms that control innate immune cell trafficking during chronic infection and inflammation, such as in tuberculosis (TB), are incompletely understood. During active TB, myeloid cells infiltrate the lung and sustain local inflammation. While the chemoattractants that orchestrate these processes are increasingly recognized, the posttranscriptional events that dictate their availability are unclear. We identified microRNA-223 (miR-223) as an upregulated small noncoding RNA in...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1172/jci67604

Authors


More by this author
Role:
Author
ORCID:
0000-0002-2283-6613
Publisher:
American Society for Clinical Investigation
Journal:
Journal of Clinical Investigation More from this journal
Volume:
123
Issue:
11
Pages:
4836-4848
Publication date:
2013-10-01
Acceptance date:
2013-08-01
DOI:
EISSN:
1558-8238
ISSN:
0021-9738
Pmid:
24084739
Language:
English
Keywords:
Pubs id:
pubs:939837
UUID:
uuid:c6f8c395-4380-4073-9498-2caf494fbf29
Local pid:
pubs:939837
Source identifiers:
939837
Deposit date:
2018-11-09

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP