- Abstract:
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Background:
Tofacitinib is an oral Janus kinase inhibitor for the treatment of psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. This study evaluated the efficacy and safety of tofacitinib 5 mg twice daily monotherapy after methotrexate withdrawal.
Methods:
Expand abstract
OPAL Balance was an open-label, long-term extension study of tofacitinib in patients with psoriatic arthritis who participated in the OPAL Broaden and OPAL Bey... - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1016/S2665-9913(20)30339-8
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- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet Rheumatology Journal website
- Publication date:
- 2020-11-16
- Acceptance date:
- 2020-08-24
- DOI:
- EISSN:
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2665-9913
- Pubs id:
-
1133215
- Local pid:
- pubs:1133215
- Language:
- English
- Keywords:
- Copyright holder:
- Elsevier
- Rights statement:
- © 2020 Elsevier Ltd. All rights reserved.
Journal article
Tofacitinib as monotherapy following methotrexate withdrawal in patients with psoriatic arthritis previously treated with open-label tofacitinib plus methotrexate: a randomised, placebo-controlled substudy of OPAL Balance
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