Journal article
Dominant tolerance and linked suppression induced by therapeutic antibodies do not depend on Fas-FasL interactions.
- Abstract:
-
BACKGROUND: Nonlytic anti-CD4 monoclonal antibody therapy can be used to induce transplantation tolerance in rodent models. Such tolerance is often associated with dominant regulation, mediated by CD4+ cells, and characterized by infectious tolerance and linked suppression. Understanding the mechanisms by which CD4+ regulatory cells function may improve the manner in which current immunosuppressants are applied and may lead to the development of new tolerance-inducing therapeutics. Fas-mediat...
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- Publication status:
- Published
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- Publisher copy:
- 10.1097/00007890-200004270-00026
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Bibliographic Details
- Journal:
- Transplantation
- Volume:
- 69
- Issue:
- 8
- Pages:
- 1683-1689
- Publication date:
- 2000-04-01
- DOI:
- EISSN:
-
1534-6080
- ISSN:
-
0041-1337
- Source identifiers:
-
14231
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:14231
- UUID:
-
uuid:c6dff07f-259d-4fa0-beb7-436a664f05dd
- Local pid:
- pubs:14231
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2000
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