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Journal article

Meta-analysis of gene-level tests for rare variant association.

Abstract:

The majority of reported complex disease associations for common genetic variants have been identified through meta-analysis, a powerful approach that enables the use of large sample sizes while protecting against common artifacts due to population structure and repeated small-sample analyses sharing individual-level data. As the focus of genetic association studies shifts to rare variants, genes and other functional units are becoming the focus of analysis. Here we propose and evaluate new a...

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Publication status:
Published

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Publisher copy:
10.1038/ng.2852

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Journal:
Nature genetics
Volume:
46
Issue:
2
Pages:
200-204
Publication date:
2014-02-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:c6dbf66c-374e-40d7-958c-26848c0c7f4c
Source identifiers:
444137
Local pid:
pubs:444137

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