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Challenges for machine learning in clinical translation of big data imaging studies

Abstract:
Combining deep learning image analysis methods and large-scale imaging datasets offers many opportunities to neuroscience imaging and epidemiology. However, despite these opportunities and the success of deep learning when applied to a range of neuroimaging tasks and domains, significant barriers continue to limit the impact of large-scale datasets and analysis tools. Here, we examine the main challenges and the approaches that have been explored to overcome them. We focus on issues relating to data availability, interpretability, evaluation, and logistical challenges and discuss the problems that still need to be tackled to enable the success of “big data” deep learning approaches beyond research.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.neuron.2022.09.012

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Oxford college:
Worcester College
Role:
Author
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Role:
Author
ORCID:
0000-0001-5970-9100
More by this author
Role:
Author
ORCID:
0000-0002-9451-4779
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0001-6043-0166


Publisher:
Cell Press
Journal:
Neuron More from this journal
Volume:
110
Issue:
23
Pages:
3866-3881
Publication date:
2022-10-10
Acceptance date:
2022-10-01
DOI:
EISSN:
1097-4199
ISSN:
0896-6273


Language:
English
Keywords:
Pubs id:
1282865
Local pid:
pubs:1282865
Deposit date:
2022-10-13
ARK identifier:

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