Journal article icon

Journal article

Advances in osteoclast biology: Old findings and new insights from mouse models

Abstract:

The maintenance of adequate bone mass is dependent upon the controlled and timely removal of old, damaged bone. This complex process is performed by the highly specialized, multinucleated osteoclast. Over the past 15 years, a detailed picture has emerged describing the origins, differentiation pathways and activation stages that contribute to normal osteoclast function. This information has primarily been obtained by the development and skeletal analysis of genetically modified mouse models. ...

Expand abstract

Actions


Access Document


Publisher copy:
10.1038/nrrheum.2011.23

Authors


Edwards, JR More by this author
Journal:
Nature Reviews Rheumatology
Volume:
7
Issue:
4
Pages:
235-243
Publication date:
2011-04-05
DOI:
EISSN:
1759-4804
ISSN:
1759-4790
URN:
uuid:c64f9457-3363-4aa5-9ce3-41626f78883b
Source identifiers:
137706
Local pid:
pubs:137706
Language:
English

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP