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Journal article

Lack of Epstein-Barr virus- and HIV-specific CD27- CD8+ T cells is associated with progression to viral disease in HIV-infection.

Abstract:

OBJECTIVE: Despite readily detectable virus-specific CD8+ T cells in most HIV-infected patients, immune surveillance is eventually lost, leading to progression to AIDS. To investigate the underlying mechanism of this loss of immune control phenotypic analysis of HIV- and Epstein-Barr virus (EBV)-specific CD8+ T cells was performed. DESIGN: In three clinically distinct groups, long-term asymptomatics, progressors to opportunistic infections and progressors to EBV-associated non-Hodgkin lymphom...

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Publication status:
Published

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Authors


van Baarle, D More by this author
Kostense, S More by this author
Hovenkamp, E More by this author
Nanlohy, N More by this author
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Journal:
AIDS (London, England)
Volume:
16
Issue:
15
Pages:
2001-2011
Publication date:
2002-10-05
DOI:
EISSN:
1473-5571
ISSN:
0269-9370
URN:
uuid:c645cad5-8189-4a43-a3ec-b6a45779cd90
Source identifiers:
38501
Local pid:
pubs:38501

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