Journal article
Does pain at an earlier stage of chondropathy protect female mice from structural progression after surgically induced osteoarthritis?
- Abstract:
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Objective Female C57BL/6 mice exhibit less severe chondropathy than male mice. This study was undertaken to test the robustness of this observation and explore underlying mechanisms.
Methods Osteoarthritis was induced in male and female C57BL/6 or DBA/1 mice (n = 6–15 per group) by destabilization of the medial meniscus (DMM) or partial meniscectomy (PMX). Some mice were ovariectomized (OVX) (n = 30). In vivo repair after focal cartilage defect or ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Supplementary materials, Version of record, 43.5KB)
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(Version of record, 1.2MB)
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- Publisher copy:
- 10.1002/art.41421
Authors
Funding
Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Arthritis & Rheumatology Journal website
- Volume:
- 72
- Issue:
- 12
- Pages:
- 2083-2093
- Publication date:
- 2020-11-04
- Acceptance date:
- 2020-06-11
- DOI:
- EISSN:
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2326-5205
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1115442
- Local pid:
- pubs:1115442
- Deposit date:
- 2020-07-03
Terms of use
- Copyright holder:
- von Loga et al.
- Copyright date:
- 2020
- Rights statement:
- © 2020 The Authors. Arthritis & Rheumatology published by Wiley Periodicals LLC on behalf of American College of Rheumatology. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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