Journal article : Review
Tuberculous meningitis in children: reducing the burden of death and disability
- Abstract:
- Tuberculous meningitis disproportionately affects young children. As the most devastating form of tuberculosis, it is associated with unacceptably high rates of mortality and morbidity even if treated. Challenging to diagnose and treat, tuberculous meningitis commonly causes long-term neurodisability in those who do survive. There remains an urgent need for strengthened surveillance, improved rapid diagnostics technology, optimised anti-tuberculosis drug therapy, investigation of new host-directed therapy, and further research on long-term functional and neurodevelopmental outcomes to allow targeted intervention. This review focuses on the neglected field of paediatric tuberculous meningitis and bridges current clinical gaps with research questions to improve outcomes from this crippling disease.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 492.6KB, Terms of use)
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- Publisher copy:
- 10.3390/pathogens11010038
Authors
- Publisher:
- MDPI
- Journal:
- Pathogens More from this journal
- Volume:
- 11
- Issue:
- 1
- Article number:
- 38
- Place of publication:
- Switzerland
- Publication date:
- 2021-12-30
- Acceptance date:
- 2021-12-21
- DOI:
- EISSN:
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2076-0817
- Pmid:
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35055986
- Language:
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English
- Keywords:
- Subtype:
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Review
- Pubs id:
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1236415
- Local pid:
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pubs:1236415
- Deposit date:
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2025-03-20
- ARK identifier:
Terms of use
- Copyright holder:
- Huynh et al
- Copyright date:
- 2021
- Rights statement:
- © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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