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Animal models.

Abstract:

Animal models of cerebral ischaemia mimic at best less than 25% of all strokes. Compounds which prove efficacious in animal models should, therefore, only be expected to improve outcome in a quarter of all strokes. If trials for acute stroke are to succeed, stroke subgroups represented by the animal models should be targeted. For the other subgroups, e.g. lacunar stroke, appropriate animal models need to be developed. Moreover, thrombolysis should be included in animal models because it is li...

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Publication status:
Published

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Publisher copy:
10.1258/0007142001903238

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Stroke and Geratology
Journal:
British medical bulletin
Volume:
56
Issue:
2
Pages:
307-317
Publication date:
2000
DOI:
EISSN:
1471-8391
ISSN:
0007-1420
URN:
uuid:c5feade5-e44c-4b68-9df3-f2e56f8d61a7
Source identifiers:
80165
Local pid:
pubs:80165

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