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Effect of brain death and non-heart-beating kidney donation on renal function and injury: an assessment in the isolated perfused rat kidney.

Abstract:

OBJECTIVES: Ischemic injury to the renal allograft prior to implantation is considered as the major cause of primary non and never-function (PNF) and delayed graft function (DGF). Evidence has been put forward that brain dead and non-heart-beating (NHB) donor organs are of marginal quality compared to living donors. The purpose of this study was to evaluate renal function and injury of brain dead and NHB donor kidneys using the isolated perfused rat kidney. MATERIAL AND METHODS: Fisher F344 ...

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Authors


van den Eijnden, MM More by this author
Leuvenink, HG More by this author
Ottens, PJ More by this author
't Hart, NA More by this author
van Oeveren, W More by this author
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Journal:
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
Volume:
1
Issue:
2
Pages:
85-95
Publication date:
2003-12-05
EISSN:
2146-8427
ISSN:
1304-0855
URN:
uuid:c5fbad87-4c56-4805-bc6a-effaeb9bd1fd
Source identifiers:
191124
Local pid:
pubs:191124

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