Journal article
Connectivity profile and function of uniquely human cortical areas
- Abstract:
- Determining the brain specializations unique to humans requires directly comparative anatomical information from other primates, especially our closest relatives. Human (Homo sapiens; m/f), chimpanzee (Pan troglodytes; f), and rhesus macaque (Macaca mulatta; m/f) white matter atlases were used to create connectivity blueprints, i.e., descriptions of the cortical grey matter in terms of the connectivity with homologous white matter tracts. This allowed a quantitative comparative of cortical organization across the species. We identified human-unique connectivity profiles concentrated in temporal and parietal cortices, and hominid-unique organization in prefrontal cortex. Functional decoding revealed human-unique hotspots correlated with language processing and social cognition. Overall, our results counter models that assign primacy to prefrontal cortex for human uniqueness.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 549.0KB, Terms of use)
-
- Publisher copy:
- 10.1523/jneurosci.2017-24.2025
Authors
+ European Research Council
More from this funder
- Funder identifier:
- https://ror.org/0472cxd90
- Grant:
- CoG 101000969
- Programme:
- Consolidator Grant
+ Wellcome Trust
More from this funder
- Funder identifier:
- https://ror.org/029chgv08
- Grant:
- 203129/Z/16/Z
+ Biotechnology and Biological Sciences Research Council
More from this funder
- Funder identifier:
- https://ror.org/00cwqg982
- Grant:
- BB/N019814/1
+ University of Oxford
More from this funder
- Funder identifier:
- https://ror.org/052gg0110
- Programme:
- E P A Cephalosporin Fund
- Publisher:
- Society for Neuroscience
- Journal:
- Journal of Neuroscience More from this journal
- Volume:
- 45
- Issue:
- 15
- Article number:
- e2017242025
- Place of publication:
- United States
- Publication date:
- 2025-03-17
- Acceptance date:
- 2025-02-15
- DOI:
- EISSN:
-
1529-2401
- ISSN:
-
0270-6474
- Pmid:
-
40097185
- Language:
-
English
- Keywords:
- Pubs id:
-
2096102
- Local pid:
-
pubs:2096102
- Deposit date:
-
2025-06-10
- ARK identifier:
Terms of use
- Copyright holder:
- Bryant et al.
- Copyright date:
- 2025
- Rights statement:
- © 2025 Bryant et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
- Licence:
- CC Attribution (CC BY)
If you are the owner of this record, you can report an update to it here: Report update to this record