Applying mouse complex-trait resources to behavioural genetics.

Journal article

Studies of the genetic basis of behaviour in mice are at a turning point. Soon, new resources will enable the behavioural function of all genes to be tested and the networks of genes, messenger RNAs and proteins involved in a particular behaviour to be identified. Using these resources, scientists will be able to analyse mouse behaviour at an unprecedented level of detail. Interpreting the new data, however, will require a shift in focus from gene-based approaches to network-based approaches.

Authors: Flint, J; Mott, R

• Publication status: Published
• Journal: Nature
• Volume: 456
• Issue: 7223
• Pages: 724-727
• Publication date: 2008-12-01
• DOI: 10.1038/nature07630
• EISSN: 1476-4687
• ISSN: 0028-0836
• Language: English
• Keywords: Mutagenesis; Mice, Knockout; Animals; Genetics, Behavioral; Behavior, Animal; Computational Biology; Phenotype; Mice