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The pestivirus E(rns) glycoprotein interacts with E2 in both infected cells and mature virions.

Abstract:

E(rns) is a pestivirus envelope glycoprotein indispensable for virus attachment and infection of target cells. Unlike the other two envelope proteins E1 and E2, E(rns) lacks a transmembrane domain and a vast quantity is secreted into the medium of infected cells. The protein is also present in fractions of pure pestivirus virions, raising the important and intriguing question regarding the mechanism of its attachment to the pestivirus envelope. In this study a direct interaction between E(rns...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Virology Journal website
Volume:
314
Issue:
2
Pages:
696-705
Publication date:
2003-08-07
Acceptance date:
2003-06-13
DOI:
EISSN:
1096-0341
ISSN:
0042-6822
URN:
uuid:c4df0c3b-d894-4a85-9305-d14dcf9d9f3a
Source identifiers:
100036
Local pid:
pubs:100036

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