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Proteomic identification of host and parasite biomarkers in saliva from patients with uncomplicated Plasmodium falciparum malaria.

Abstract:

BACKGROUND: Malaria cases attributed to Plasmodium falciparum account for approximately 600,000 deaths yearly, mainly in African children. The gold standard method to diagnose malaria requires the visualization of the parasite in blood. The role of non-invasive diagnostic methods to diagnose malaria remains unclear. METHODS: A protocol was optimized to deplete highly abundant proteins from saliva to improve the dynamic range of the proteins identified and assess their suitability as candidat...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1475-2875-11-178

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Funding agency for:
Casals-Pascual, C
Grant:
G0701885
Publisher:
BioMed Central Publisher's website
Journal:
Malaria journal Journal website
Volume:
11
Issue:
1
Article number:
178
Publication date:
2012-01-01
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
Source identifiers:
334693
Language:
English
Keywords:
UUID:
uuid:c4a073f6-db93-4d52-aea1-c4761e9206dd
Local pid:
pubs:334693
Deposit date:
2012-12-19

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