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Journal article

Glycosylation is an androgen-regulated process essential for prostate cancer cell viability.

Abstract:

Steroid androgen hormones play a key role in the progression and treatment of prostate cancer, with androgen deprivation therapy being the first-line treatment used to control cancer growth. Here we apply a novel search strategy to identify androgen-regulated cellular pathways that may be clinically important in prostate cancer. Using RNASeq data, we searched for genes that showed reciprocal changes in expression in response to acute androgen stimulation in culture, and androgen deprivation i...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.ebiom.2016.04.018

Authors


Munkley, J More by this author
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ORCID:
0000-0003-0015-6577
Livermore, KE More by this author
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ORCID:
0000-0003-0167-8393
Wilson, BT More by this author
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J. G. W Patterson Foundation More from this funder
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Publisher:
Elsevier Publisher's website
Journal:
EBioMedicine Journal website
Volume:
8
Pages:
103-116
Publication date:
2016-04-05
Acceptance date:
2016-04-15
DOI:
EISSN:
2352-3964
ISSN:
2352-3964
Pubs id:
pubs:817477
URN:
uri:c489f4cd-4387-4f10-8afd-2db6a1c0ae04
UUID:
uuid:c489f4cd-4387-4f10-8afd-2db6a1c0ae04
Local pid:
pubs:817477

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