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Assessment of three antibiotic combination regimens against Gram-negative bacteria causing neonatal sepsis in low- and middle-income countries

Abstract:

Gram-negative bacteria (GNB) are a major cause of neonatal sepsis in low- and middle-income countries (LMICs). Although the World Health Organization (WHO) reports that over 80% of these sepsis deaths could be prevented through improved treatment, the efficacy of the currently recommended first- and second-line treatment regimens for this condition is increasingly affected by high rates of drug resistance. Here we assess three well known antibiotics, fosfomycin, flomoxef and amikacin, in comb...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41467-024-48296-z

Authors


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Role:
Author
ORCID:
0000-0003-4054-8372
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Role:
Author
ORCID:
0000-0002-5897-0240
Publisher:
Springer Nature
Journal:
Nature Communications More from this journal
Volume:
15
Issue:
1
Article number:
3947
Publication date:
2024-05-10
Acceptance date:
2024-04-26
DOI:
EISSN:
2041-1723
Language:
English
Pubs id:
1995470
Local pid:
pubs:1995470
Deposit date:
2024-05-11

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