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Blister fluid for the diagnosis of subepidermal immunobullous diseases: a comparative study of basement membrane zone autoantibodies detected in blister fluid and serum.

Abstract:

The subepidermal immunobullous diseases bullous pemphigoid (BP), cicatricial pemphigoid (CP), pemphigoid gestationis (PG) and linear IgA disease (LAD) are characterized by circulating and in vivo deposition of antibodies to antigens in the cutaneous basement membrane zone (BMZ). Indirect immunofluorescence (IMF) of serum is a routine diagnostic test to detect circulating BMZ antibodies in these diseases. We have compared the titres of IgG and IgA and their subclasses, also of IgM and IgE BMZ ...

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Publication status:
Published

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Volume:
139
Issue:
1
Pages:
27-32
Publication date:
1998-07-05
DOI:
EISSN:
1365-2133
ISSN:
0007-0963
URN:
uuid:c3a2ac61-f32d-4050-98bf-266f995fa768
Source identifiers:
8315
Local pid:
pubs:8315

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