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Blister fluid for the diagnosis of subepidermal immunobullous diseases: a comparative study of basement membrane zone autoantibodies detected in blister fluid and serum.

Abstract:

The subepidermal immunobullous diseases bullous pemphigoid (BP), cicatricial pemphigoid (CP), pemphigoid gestationis (PG) and linear IgA disease (LAD) are characterized by circulating and in vivo deposition of antibodies to antigens in the cutaneous basement membrane zone (BMZ). Indirect immunofluorescence (IMF) of serum is a routine diagnostic test to detect circulating BMZ antibodies in these diseases. We have compared the titres of IgG and IgA and their subclasses, also of IgM and IgE BMZ ...

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Publication status:
Published

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Volume:
139
Issue:
1
Pages:
27-32
Host title:
The British journal of dermatology
Publication date:
1998-07-01
Event location:
ENGLAND
DOI:
EISSN:
1365-2133
ISSN:
0007-0963
Source identifiers:
8315

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