- Abstract:
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Background: The size of any causal contribution of central and general adiposity to chronic kidney disease (CKD) risk and the underlying mechanism of mediation are unknown.
Methods: 281,228 UK Biobank participants were included in estimates of the relevance of waist-to-hip ratio and body-mass index (BMI) to CKD prevalence. Conventional approaches used logistic regression. Genetic analyses employed Mendelian Randomisation and data from 394 waist-to-...
Expand abstract - Publication status:
- Accepted
- Peer review status:
- Peer reviewed
- Files:
-
- Publisher copy:
- 10.1681/ASN.2020050679
-
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- Publisher:
- American Society of Nephrology Publisher's website
- Journal:
- Journal of the American Society of Nephrology Journal website
- Publication date:
- 2020-10-30
- Acceptance date:
- 2020-09-09
- DOI:
- EISSN:
-
1533-3450
- ISSN:
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1046-6673
- Pubs id:
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1132498
- Local pid:
- pubs:1132498
- Language:
- English
- Keywords:
- Copyright holder:
- American Society of Nephrology
- Copyright date:
- 2021
- Rights statement:
- © 2021 by the American Society of Nephrology
- License:
- CC Attribution (CC BY)
Journal article
Conventional and genetic evidence on the association between adiposity and chronic kidney disease
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