Journal article icon

Journal article

The use of patient-reported outcome measures to guide referral for hip and knee arthroplasty: part 2: a cost-effectiveness analysis

Abstract:

Aims To assess how the cost-effectiveness of total hip arthroplasty (THA) and total knee arthroplasty (TKA) varies with age, sex, and preoperative Oxford Hip or Knee Score (OHS/OKS); and to identify the patient groups for whom THA/TKA is cost-effective.

Methods We conducted a cost-effectiveness analysis using a Markov model from a United Kingdom NHS perspective, informed by published analyses of patient-level data. We assessed the cost-effectiveness of THA and TKA in adults with hip or knee osteoarthritis compared with having no arthroplasty surgery during the ten-year time horizon.

Results THA and TKA cost < £7,000 per quality-adjusted life-year (QALY) gained at all preoperative scores below the absolute referral thresholds calculated previously (40 for OHS and 41 for OKS). Furthermore, THA cost < £20,000/QALY for patients with OHS of ≤ 45, while TKA was cost-effective for patients with OKS of ≤ 43, since the small improvements in quality of life outweighed the cost of surgery and any subsequent revisions. Probabilistic and one-way sensitivity analyses demonstrated that there is little uncertainty around the conclusions.

Conclusion If society is willing to pay £20,000 per QALY gained, THA and TKA are cost-effective for nearly all patients who currently undergo surgery, including all patients at and above our calculated absolute referral thresholds.

Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1302/0301-620X.102B7.BJJ-2019-0105.R2

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Role:
Author
ORCID:
0000-0003-3255-748X
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Role:
Author
ORCID:
0000-0003-0239-7278
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author


Publisher:
British Editorial Society of Bone and Joint Surgery
Journal:
Bone and Joint Journal More from this journal
Volume:
102-B
Issue:
7
Pages:
950–958
Publication date:
2020-06-30
Acceptance date:
2020-02-04
DOI:
EISSN:
2049-4408
ISSN:
2049-4394


Language:
English
Keywords:
Pubs id:
1084793
Local pid:
pubs:1084793
Deposit date:
2020-02-04

Terms of use



Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP