Journal article
Mosaic loss of chromosome Y in blood is associated with Alzheimer disease
- Abstract:
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Men have a shorter life expectancy compared with women but the underlying factor(s) are not clear. Late-onset, sporadic Alzheimer disease (AD) is a common and lethal neurodegenerative disorder and many germline inherited variants have been found to influence the risk of developing AD. Our previous results show that a fundamentally different genetic variant, i.e., lifetime-acquired loss of chromosome Y (LOY) in blood cells, is associated with all-cause mortality and an increased risk of non-he...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.0MB)
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- Publisher copy:
- 10.1016/j.ajhg.2016.05.014
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Authors
Funding
Bibliographic Details
- Publisher:
- Cell Press Publisher's website
- Journal:
- American journal of human genetics Journal website
- Volume:
- 98
- Issue:
- 6
- Pages:
- 1208-1219
- Publication date:
- 2016-06-02
- Acceptance date:
- 2016-05-09
- DOI:
- EISSN:
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1537-6605
- ISSN:
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0002-9297
- Source identifiers:
-
624923
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:624923
- UUID:
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uuid:c3643c04-5c0f-4ab2-bb0c-dc576e1b8d60
- Local pid:
- pubs:624923
- Deposit date:
- 2016-06-15
Terms of use
- Copyright holder:
- Dumanski et al
- Copyright date:
- 2016
- Notes:
- © 2016 The Author(s).
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