Journal article
PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma
- Abstract:
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Background: PIM serine/threonine kinases are often highly expressed in haematological malignancies. We have shown that PIM inhibitors reduced the survival and migration of leukaemic cells. Here, we investigated PIM kinases in diffuse large B-cell lymphoma (DLBCL) biopsy samples and DLBCL cell lines.Methods:Immunohistochemical staining for PIM kinases and CXCR4 was performed on tissue microarrays from a cohort of 101 DLBCL cases, and the effects of PIM inhibitors on the survival and migration ...
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- Publisher copy:
- 10.1038/bjc.2012.272
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Authors
Bibliographic Details
- Journal:
- British Journal of Cancer
- Volume:
- 107
- Issue:
- 3
- Pages:
- 491-500
- Publication date:
- 2012-07-24
- DOI:
- EISSN:
-
1532-1827
- ISSN:
-
0007-0920
- Source identifiers:
-
348837
Item Description
- Pubs id:
-
pubs:348837
- UUID:
-
uuid:c3400496-b2e4-470b-8e3f-2dc7b48c18bd
- Local pid:
- pubs:348837
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2012
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