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Journal article

Early gamma interferon and interleukin-2 responses to vaccination predict the late resting memory in malaria-naive and malaria-exposed individuals.

Abstract:

Two different cell populations respond to potent T-cell-inducing vaccinations. The induction and loss of effector cells can be seen using an ex vivo enzyme-linked immunospot (ELISPOT) assay, but the more durable resting memory response is demonstrable by a cultured ELISPOT assay. The relationship of the early effector response to durable resting memory is incompletely understood. Effector phenotype is usually identified by gamma interferon (IFN-gamma) production, but interleukin-2 (IL-2) has ...

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Publication status:
Published

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Publisher copy:
10.1128/iai.00774-06

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Role:
Author
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Journal:
Infection and immunity
Volume:
74
Issue:
11
Pages:
6331-6338
Publication date:
2006-11-05
DOI:
EISSN:
1098-5522
ISSN:
0019-9567
URN:
uuid:c3047aa7-e089-4e18-890e-eeb043743b67
Source identifiers:
40132
Local pid:
pubs:40132

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