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Journal article

Functional heterogeneity within the developing zebrafish epicardium

Abstract:

The epicardium is essential during cardiac development, homeostasis, and repair, and yet fundamental insights into its underlying cell biology, notably epicardium formation, lineage heterogeneity, and functional cross-talk with other cell types in the heart, are currently lacking. In this study, we investigated epicardial heterogeneity and the functional diversity of discrete epicardial subpopulations in the developing zebrafish heart. Single-cell RNA sequencing uncovered three epicardial sub...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.devcel.2020.01.023

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Publisher:
Cell Press
Journal:
Developmental Cell More from this journal
Volume:
52
Issue:
5
Pages:
574-590.e6
Publication date:
2020-02-20
Acceptance date:
2020-01-22
DOI:
ISSN:
1534-5807
Language:
English
Keywords:
Pubs id:
1085095
Local pid:
pubs:1085095
Deposit date:
2020-02-20

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