Resuscitation of non-vigorous neonates born through meconium-stained amniotic fluid: post policy change impact analysis

Journal article

Background: We investigated the impact of policy change in delivery room resuscitation from routine endotracheal (ET) suctioning of non-vigorous neonates born through meconium-stained amniotic fluid (MSAF) to immediate non-invasive respiratory support.

Design: Single-centre cohort study. Prospective group (October 2016–September 2017)—non-vigorous neonates born through MSAF managed according to the current (2015) guidance of commencing respiratory support without prior suctioning. Retrospective group (August 2015–July 2016)—non-vigorous neonates born through MSAF who underwent routine ET suctioning.

Results: 1138 neonates born through MSAF were analysed. No differences in the incidence of meconium aspiration syndrome (MAS), requirement of mechanical ventilation, inhaled nitric oxide or surfactant therapy were found between groups. Less neonatal intensive care unit (NICU) admissions were necessary in the prospective cohort compared with the retrospective group (19.1% vs 55.6%, respectively; p<0.05).

Conclusion: The policy change towards not routinely suctioning non-vigorous neonates born through MSAF at birth was not associated with an increase in the local incidence of MAS and was associated with fewer NICU admissions.

Authors: Oommen, VI; Ramaswamy, VV; Szyld, E; Roehr, CC

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: BMJ Publishing Group
• Journal: Archives of Disease in Childhood. Fetal and Neonatal Edition
• Volume: 106
• Issue: 3
• Pages: 324-326
• Publication date: 2020-09-22
• Acceptance date: 2020-09-08
• DOI: 10.1136/archdischild-2020-319771
• EISSN: 1468-2052
• ISSN: 1359-2998
• Pmid: 32963086
• Language: English
• Keywords: practice guidelines as topic; meconium aspiration syndrome; incidence; policy making; resuscitation; humans; amniotic fluid; outcome and process assessment; meconium; suction; noninvasive ventilation; FFR; health services research; United Kingdom; infant, newborn; delivery, obstetric; intensive care units, neonatal