Journal article icon

Journal article

Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man.

Abstract:

The steady-state basal plasma glucose and insulin concentrations are determined by their interaction in a feedback loop. A computer-solved model has been used to predict the homeostatic concentrations which arise from varying degrees beta-cell deficiency and insulin resistance. Comparison of a patient's fasting values with the model's predictions allows a quantitative assessment of the contributions of insulin resistance and deficient beta-cell function to the fasting hyperglycaemia (homeosta...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1007/bf00280883

Authors


Expand authors...
Publisher:
Springer-Verlag
Journal:
Diabetologia
Volume:
28
Issue:
7
Pages:
412-419
Publication date:
1985-07-05
DOI:
EISSN:
1432-0428
ISSN:
0012-186X
URN:
uuid:c2684951-211f-4515-aade-c3c9d6dc7377
Source identifiers:
72990
Local pid:
pubs:72990

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP