Journal article
Enantioselective organocatalytic Michael addition of malonate esters to nitro olefins using bifunctional cinchonine derivatives.
- Abstract:
- A family of 9-amino(9-deoxy) epicinchonine derivatives, possessing a range of mono- and bidentate hydrogen bond donor groups at the 9-position, were synthesised and evaluated for asymmetric organocatalytic activity in the dimethyl malonate Michael addition to beta-nitrostyrene; thiourea derivative was identified as the most effective bifunctional organic catalyst and found to induce high enantioselectivity in the malonate ester Michael addition reaction to a range of nitro olefins.
- Publication status:
- Published
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Authors
- Journal:
- Chemical Communications More from this journal
- Issue:
- 35
- Pages:
- 4481-4483
- Publication date:
- 2005-09-01
- DOI:
- EISSN:
-
1364-548X
- ISSN:
-
1359-7345
- Language:
-
English
- Pubs id:
-
pubs:33218
- UUID:
-
uuid:c20493d8-b06c-4cd7-a0a7-73edea552500
- Local pid:
-
pubs:33218
- Source identifiers:
-
33218
- Deposit date:
-
2012-12-19
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- Copyright date:
- 2005
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