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Ion microscope imaging mass spectrometry using a Timepix3-based optical camera

Abstract:

Ion microscopy allows for high-throughput mass spectrometry imaging. In order to resolve congested mass spectra, a high degree of timing precision is required from the microscope detector. In this paper we present an ion microscope mass spectrometer that uses a Timepix3 hybrid pixel readout with an optimal 1.56 ns resolution. A novel triggering technique is also employed to remove the need for an external time-to-digital converter (TDC) and allow the experiment to be performed using a low-cos...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1021/jasms.2c00223

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Oxford college:
Jesus College
Role:
Author
ORCID:
0000-0003-3421-0850
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Name:
Engineering and Physical Sciences Research Council
Grant:
EP/L005913/1
Ref R102215-101 (EP/V026690/1)
Publisher:
American Chemical Society
Journal:
Journal of the American Society for Mass Spectrometry More from this journal
Volume:
33
Issue:
12
Pages:
2328-2332
Publication date:
2022-11-16
Acceptance date:
2022-11-02
DOI:
EISSN:
1879-1123
ISSN:
1044-0305
Language:
English
Keywords:
Pubs id:
1304668
Local pid:
pubs:1304668
Deposit date:
2022-11-18

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