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Thesis

Estimation of Plasmodium falciparum allele and multi-SNP haplotype and genotype frequencies

Subtitle:
Estimation of malaria haplotype frequencies
Abstract:

Malaria kills hundreds of thousands of people each year, yet is entirely curable given prompt treatment. Malaria parasites evolve resistance to antimalarial drugs, hence routine surveillance of antimalarial resistance is vital. The surveillance of parasite genetic markers of resistance provides an economical adjunct to clinical efficacy trials, and has the potential to resolve drug specific resistance ahead of clinical failure. To monitor spatiotemporal changes using genetic markers, frequ...

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Department:
Doctoral Training Centre - MPLS

Contributors

Department:
Human Genetics WT Centre
Role:
Examiner
Department:
Harvard T.H. Chan School of Public Health
Role:
Examiner
Department:
Statistics
Role:
Supervisor
Department:
Tropical Medicine
Role:
Supervisor
Department:
School of Mathematical Sciences at Monash University
Role:
Supervisor
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Grant:
Oxford Systems Biology Doctoral Training Centre
Funding agency for:
Project
Type of award:
DPhil
Awarding institution:
University of Oxford

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