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Distinct determinants of human immunodeficiency virus type 1 RNA and DNA loads in vaginal and cervical secretions.

Abstract:

The relationship between human immunodeficiency virus type 1 (HIV-1) viral RNA and proviral DNA load in vagina and cervix and that found in the plasma and peripheral blood mononuclear cells (PBMC) was investigated in 28 HIV-1-infected women. Of the patients, 64% had > or = 1 HIV-1 RNA-positive genital sample, while 71% had > or = 1 DNA-positive sample. The higher the cervical HIV load, the more widespread was the virus in the genital tract. A strong correlation was found between viral R...

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Publisher copy:
10.1086/515266

Authors


Iversen, AK More by this author
Larsen, AR More by this author
Balslev, U More by this author
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Journal:
The Journal of infectious diseases
Volume:
177
Issue:
5
Pages:
1214-1220
Publication date:
1998-05-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:c1657514-4820-4511-9bbc-a7cd96149cc8
Source identifiers:
68279
Local pid:
pubs:68279

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