Journal article
Plasmodium falciparum Variant Surface Antigen Expression Patterns during Malaria
- Abstract:
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The variant surface antigens expressed on Plasmodium falciparum-infected erythrocytes are potentially important targets of immunity to malaria and are encoded, at least in part, by a family of var genes, about 60 of which are present within every parasite genome. Here we use semi-conserved regions within short var gene sequence "tags" to make direct comparisons of var gene expression in 12 clinical parasite isolates from Kenyan children. A total of 1,746 var clones were sequenced from genomic...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 729.7KB, Terms of use)
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- Publisher copy:
- 10.1371/journal.ppat.0010026
Authors
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PLoS Pathog More from this journal
- Volume:
- 1
- Issue:
- 3
- Pages:
- e26
- Publication date:
- 2005-11-18
- DOI:
- EISSN:
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1553-7374
- ISSN:
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1553-7366
Item Description
- Language:
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English
- Keywords:
- UUID:
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uuid:c14f5aba-15da-4512-9072-1c69d54b04cc
- Local pid:
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pubs:9358
- Source identifiers:
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9358
- Deposit date:
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2012-12-19
Terms of use
- Copyright holder:
- Bull et al
- Copyright date:
- 2005
- Notes:
- Last author. It is the first major paper looking at variant antigen expression in malaria in the field on a large scale. I initiated and was overseeing all the work in this paper and made significant contributions to the analysis. © 2005 Bull et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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