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Relationship between chromosome 18q status and colorectal cancer prognosis: a prospective, blinded analysis of 280 patients.

Abstract:

BACKGROUND: The relationship between chromosome 18q allelic imbalance (AI) and survival in colorectal cancer (CRC) is unclear, and study design may have contributed to inconsistent results previously reported. PATIENTS AND METHODS: Two hundred and eighty tumours from CRC patients participating in a molecular sub-study from a single multicentre trial of adjuvant intra-portal 5-fluorouracil were genotyped at 5 chromosome 18q microsatellite markers, blinded to clinical data and prospective to f...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit, BHF Centre of Research Excellence
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Journal:
Anticancer research
Volume:
27
Issue:
1B
Pages:
627-633
Publication date:
2007
EISSN:
1791-7530
ISSN:
0250-7005
URN:
uuid:c115f8df-7d00-4189-814d-923d2ba25853
Source identifiers:
79312
Local pid:
pubs:79312

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