Relationship between chromosome 18q status and colorectal cancer prognosis: a prospective, blinded analysis of 280 patients.

Popat, S; Zhao, D; Chen, Z; Pan, H; Shao, Y; Chandler, I; Houlston, RS

Abstract:

BACKGROUND: The relationship between chromosome 18q allelic imbalance (AI) and survival in colorectal cancer (CRC) is unclear, and study design may have contributed to inconsistent results previously reported. PATIENTS AND METHODS: Two hundred and eighty tumours from CRC patients participating in a molecular sub-study from a single multicentre trial of adjuvant intra-portal 5-fluorouracil were genotyped at 5 chromosome 18q microsatellite markers, blinded to clinical data and prospective to f...

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APA Style

Popat, S., Zhao, D., Chen, Z., Pan, H., Shao, Y., Chandler, I., & Houlston, R. S. (2007). Relationship between chromosome 18q status and colorectal cancer prognosis: a prospective, blinded analysis of 280 patients. Anticancer Research, 27(1B), 627–633.

MLA Style

Popat, S., et al. “Relationship between Chromosome 18q Status and Colorectal Cancer Prognosis: a Prospective, Blinded Analysis of 280 Patients.” Anticancer Research, vol. 27, no. 1B, Anticancer research, 2007, pp. 627–33.

Chicago Style

Popat, S, D Zhao, Z Chen, H Pan, Y Shao, I Chandler, and RS Houlston. 2007. “Relationship between Chromosome 18q Status and Colorectal Cancer Prognosis: a Prospective, Blinded Analysis of 280 Patients.” Anticancer Research 27 (1B): 627–33.
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Authors

Popat, S More by this author

Zhao, D More by this author

+ Chen, Z More by this author

Institution:

University of Oxford

Department:

Oxford, MSD, Clinical Trial Service Unit, BHF Centre of Research Excellence

Pan, H More by this author

Shao, Y More by this author

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Bibliographic Details

Journal:: Anticancer research
Volume:: 27
Issue:: 1B
Pages:: 627-633
Publication date:: 2007
EISSN:: 1791-7530
ISSN:: 0250-7005
URN:: uuid:c115f8df-7d00-4189-814d-923d2ba25853
Source identifiers:: 79312
Local pid:: pubs:79312

Item Description

Language:: English
Keywords:: Male

Colorectal Neoplasms

Aged

Chromosomes, Human, Pair 18

Prospective Studies

Prognosis

Middle Aged

Kaplan-Meier Estimate

Humans

Microsatellite Repeats

Allelic Imbalance

Adult

Adolescent

Double-Blind Method

Female

Genotype

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