Journal article icon

Journal article

Decreased hepcidin levels are associated with low steady-state hemoglobin in children with sickle cell disease in Tanzania

Abstract:
Background The contribution of hepcidin as a regulator of iron metabolism & erythropoiesis on the severity of anemia in sickle cell disease (SCD) remains poorly characterized, especially in Sub-Saharan African populations. The aims of the study were to determine if hepcidin is associated with severity of steady-state anemia in SCD and to investigate factors associated with hepcidin and anemia in SCD. Methods Archived samples from 199 Tanzanian children, ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1016/j.ebiom.2018.07.024

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
RDM - Investigative Medicine Division
ORCID:
0000-0001-5977-6602
Expand authors...
More from this funder
Funding agency for:
Armitage, AE
More from this funder
Funding agency for:
Drakesmith, H
More from this funder
Grant:
094780, 080025, 095009 and 070114
Expand funders...
Publisher:
Elsevier Publisher's website
Journal:
EBioMedicine Journal website
Volume:
34
Pages:
158-164
Publication date:
2018-07-25
Acceptance date:
2018-07-17
DOI:
ISSN:
2352-3964
Pubs id:
pubs:892310
URN:
uri:c0c31632-3bc3-499e-b09e-ced1aed42ba2
UUID:
uuid:c0c31632-3bc3-499e-b09e-ced1aed42ba2
Local pid:
pubs:892310

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP