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Journal article

Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment

Abstract:
SummaryIn the randomised TARGIT-A trial, risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy was non-inferior to whole-breast external beam radiotherapy, for local recurrence. In the long-term, no difference was found in any breast cancer outcome, whereas there were fewer deaths from non-breast-cancer causes. TARGIT-IORT should be included in pre-operative consultations with eligible patients.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41416-020-01233-5

Authors

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Role:
Author
ORCID:
0000-0003-1760-1278
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Role:
Author
ORCID:
0000-0002-8033-6123
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Role:
Author
ORCID:
0000-0001-8837-5920


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Funder identifier:
10.13039/100011088
Grant:
-
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Funder identifier:
10.13039/501100000664
Grant:
HTA 07/60/49
HTA 10/04/07
HTA 14/49/13


Publisher:
Springer Nature [academic journals on nature.com]
Journal:
British Journal of Cancer More from this journal
Volume:
124
Issue:
9
Pages:
1469-1474
Publication date:
2021-02-02
DOI:
EISSN:
1532-1827
ISSN:
0007-0920


Language:
English
Keywords:
Pubs id:
1161442
Local pid:
pubs:1161442
Source identifiers:
W3127009987
Deposit date:
2026-02-13
ARK identifier:
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