Hybrid assemblies are highly valuable for studies of Enterobacteriaceae due to their ability to fully resolve the structure of mobile genetic elements, such as plasmids, which are involved in the carriage of clinically important genes (e.g. those involved in antimicrobial resistance/virulence). The widespread application of this technique is currently primarily limited by cost. Recent data have suggested that non-inferior, and even superior, hybrid assemblies can be produced using a fraction ...Expand abstract
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- Peer reviewed
- Copyright holder:
- Lipworth, S et al.
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- © 2020 The Authors. This is an Open Access article published by the Microbiology Society under the Creative Commons Attribution License.
- CC Attribution (CC BY)
Optimised use of Oxford nanopore flowcells for hybrid assemblies
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