Journal article
Variations in alveolar partial pressure for carbon dioxide and oxygen have additive not synergistic acute effects on human pulmonary vasoconstriction.
- Abstract:
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The human pulmonary vasculature constricts in response to hypercapnia and hypoxia, with important consequences for homeostasis and adaptation. One function of these responses is to direct blood flow away from poorly-ventilated regions of the lung. In humans it is not known whether the stimuli of hypercapnia and hypoxia constrict the pulmonary blood vessels independently of each other or whether they act synergistically, such that the combination of hypercapnia and hypoxia is more effective th...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 984.1KB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0067886
Authors
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PloS one More from this journal
- Volume:
- 8
- Issue:
- 7
- Pages:
- e67886
- Publication date:
- 2013-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:418520
- UUID:
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uuid:c01c86a7-f5fc-4263-be99-427f41a06df8
- Local pid:
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pubs:418520
- Source identifiers:
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418520
- Deposit date:
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2013-11-16
Terms of use
- Copyright holder:
- Croft et al
- Copyright date:
- 2013
- Notes:
- Copyright © 2013 Croft et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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