Thesis
Fluorogenic DNA probes for single-molecule fluorescence imaging in vitro and in vivo
- Abstract:
-
The “high concentration barrier”, describing the maximum concentration of fluorescent species tolerable, is one of the main limitations of single-molecule fluorescence (SMF) measurements. Addressing this fundamental limit can enable and expand several in vitro and in vivo single-molecule applications, including tracking in crowded environments, fast super-resolution imaging, and single-molecule fluorescence resonance energy transfer (smFRET) experiments.
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Authors
Contributors
+ Kapanidis, A
- Institution:
- University of Oxford
- Division:
- MPLS
- Department:
- Physics
- Sub department:
- Condensed Matter Physics
- Oxford college:
- St Cross College
- Role:
- Supervisor
- ORCID:
- 0000-0002-0904-5323
+ Engineering and Physical Sciences Research Council
More from this funder
- Funder identifier:
- https://ror.org/0439y7842
- Funding agency for:
- Kummerlin, M
- Grant:
- 2440758
- Programme:
- EPSRC studentship
+ BIF
More from this funder
- Funder identifier:
- https://ror.org/00dkye506
- Funding agency for:
- Kummerlin, M
- Programme:
- PhD Fellowship
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Subjects:
- Deposit date:
-
2025-08-02
Terms of use
- Copyright holder:
- Mirjam Kümmerlin
- Copyright date:
- 2024
- Licence:
- CC Attribution-ShareAlike (CC BY-SA)
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