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Effect of potassium on ventilation in the rhesus monkey.

Abstract:

Increasing the concentration of arterial plasma K+ to 6-8 mM increased ventilation in two sedated analgesic-treated rhesus monkeys who had their end-tidal CO2 held constant during euoxia (arterial oxygen pressure, Pa,O2, ca 100 Torr) and hypoxia (Pa,O2, ca 40 Torr). During euoxia and hypoxia, hyperkalaemia increased ventilation up to 40 and 250%, respectively. This effect was reduced in euoxia and virtually abolished in hypoxia following an abrupt switch to 100% oxygen. Thus the ventilatory r...

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Publication status:
Published

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Authors


Paterson, DJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Bergel, DH More by this author
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Journal:
Experimental physiology
Volume:
77
Issue:
1
Pages:
217-220
Publication date:
1992-01-05
EISSN:
1469-445X
ISSN:
0958-0670
URN:
uuid:bfe3094e-6ae6-4070-a69c-282a9a171910
Source identifiers:
114037
Local pid:
pubs:114037

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