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Spectral and phase-amplitude coupling signatures in human deep brain oscillations during propofol-induced anaesthesia

Abstract:

Background: Both the cerebral cortex and subcortical structures play important roles in consciousness. Some evidence points to general anaesthesia-induced unconsciousness being associated with distinct patterns of superficial cortical electrophysiological oscillations, but how general anaesthetics influence deep brain neural oscillations and interactions between oscillations in humans is poorly understood. Methods: Local field potentials were recorded in discrete deep brain regions, including...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1016/j.bja.2018.04.031

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
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National Institute of Health Research More from this funder
Charles Wolfson Charitable Trust More from this funder
Norman Collisson Foundation More from this funder
Publisher:
Elsevier Publisher's website
Journal:
British Journal of Anaesthesia Journal website
Volume:
121
Issue:
1
Pages:
303-313
Publication date:
2018-05-25
Acceptance date:
2018-04-30
DOI:
EISSN:
1471-6771
ISSN:
0007-0912
Pubs id:
pubs:854654
URN:
uri:bfa551eb-0f8b-41d4-aa73-fcd91bf4f8ed
UUID:
uuid:bfa551eb-0f8b-41d4-aa73-fcd91bf4f8ed
Local pid:
pubs:854654

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